September 4, 2020

Mechanism of Action: Does it matter?

Understanding the mechanism of action (MOA) of a medication can prove beneficial in understanding how the drug will behave. It also helps determine the potential for […]
August 28, 2020

Errors with Half Life Determination

Calculating elimination rate constants and half lives can be challenging in patients that are unstable. For drugs that are eliminated renally, it is important to ensure […]
August 21, 2020

Revisiting Once Daily Dosing

  Recently we were asked to evaluate a patient  who was administered gentamicin 440 mg IV q24 hr. The patient received 5 doses prior to obtaining […]
August 14, 2020

Avoiding Medication Errors

An unfortunate part of healthcare involves medication errors which can occur during any phase of the distributive process. Healthcare providers are encouraged to practice Continuous Quality […]
August 7, 2020

Serotonin Syndrome: Are we missing it?

Serotonin syndrome can often go overlooked even though it can be lifethreatening if not detected in time and properly treated. The condition is caused by excessive […]
May 6, 2020

Reducing Medication Errors

Most hospitals practice continuous quality improvement and therefore have some type of medication error program in place. In many instances, we find that hospitals have an […]
April 22, 2020

Errors with Volume of Distribution

In my experiences with dosing, antibiotics tend to offer the greatest challenge, especially in septic patients. The reason this is a challenge is because septic patients […]
April 1, 2020

Assessing Probability

There are a number of methods used to assess the probability of an event resulting from medication administration. The Naranjo Scale is perhaps the most common […]
April 1, 2020

Practical steps to reduce med errors

 By focusing on five key rules of medication therapy, clinicians can reduce the occurrence of medication errors and improve patient safety. These key rules include the […]
March 25, 2020

Pharmacokinetic Dosing Errors

Medication errors associated with pharmacokinetics can sometimes get overlooked. Oftentimes, dosing errors occur but may go unreported. This can be especially true when dealing with aminoglycosides. […]
March 18, 2020

Medication Error Rates

According to ISMP, “A national or other regional medication error rate does not exist. It is not possible to establish a national medication error rate or […]
March 4, 2020

Assessing Causation: Disease or Drug?

Assessing cause and effect can often be challenging in a medical malpractice case. However, when the suspected cause involves a medication, the analysis is typically straightforward. […]
February 26, 2020

Serotonin Syndrome: A Case Review

  Previously we were asked to evaluate a 50 year old patient who was admitted for chest pain and SOB. The patient had a prior history […]